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Type 1 Diabetes Drug Developed That Could Replace Classic Injection

Scientists at Yale University have fostered another oral medication for type 1 diabetes. In mouse trials, the medication can rapidly control insulin levels, yet in addition reestablish metabolic capacity and reverse inflammation, opening up an expected way for illness counteraction.

Type 1 diabetes starts when an individual's immune cells assaults and obliterates the beta cells in the pancreas. These cells are answerable for the creation of insulin, which changes over glucose into energy, so patients need to infuse insulin on numerous occasions a day.

Taking oral insulin pills is easier and less obtrusive, however insulin is annihilated in the stomach before it enters the circulation system. Many researchers are testing different strategies to assist it with getting by, including defensive coatings, containers with microneedles, direct infusion of insulin through the stomach wall, and even nanoparticles entering the blood that discharge insulin just when glucose levels are high.

For this new research, Yale University scientists have fostered a new nanoparticle drug carrier that not exclusively can securely convey insulin to the pancreas, yet the actual packaging likewise has a remedial impact. It is made of ursodeoxycholic corrosive, which is a bile corrosive that is normally created in the body, and scientists total it. This assists it with bettering tie to receptors in the pancreas, work on metabolic capacity, and above all, even decrease the invulnerable cells that annihilate β cells in any case.

The group tried nanoparticles in mice with type 1 diabetes and observed that they can increase insulin levels, while bile corrosive nanoparticles can diminish aggravation and reestablish metabolic capacity. The group additionally observed that insulin administrated by means of oral cases was multiple times quicker than insulin taken through standard subcutaneous infusions. Significantly, comparative outcomes were found in tests on pigs.

The outcomes are extremely encouraging, obviously, more work should be done to explore whether people will see similar advantages. The group said that nanoparticles can likewise be utilized to convey different atoms and may assist with treating different infections.

The study was distributed in the diary Nature Biomedical Engineering.

via: NewAtlas.com

Winamp Is Ready For A Spectacular Comeback. The 90s' App Comes Back With A New Look

Long before the advent of music streaming services, if you wanted to listen to music on your PC, you had to download it or extract it from an audio source, such as a CD. In addition, a music player was needed at that time, and Winamp was widely known and used.

Nowadays, with new platforms like iTunes and other streaming services, the need for a media player is non-existent. However, it looks like Winamp is poised to make a comeback, according to an announcement from AudioValley, owner and parent company of WinAmp, looking to bring it back to the forefront.

However, if you thought you might see the media player revived in its original form, that might not be the case. According to the description on their website: We're building Winamp for the next generation. Not just updated, but completely revamped.

The New Winamp connects you to your music wherever you are. Brings you closer to the artists you love. You can find your favorite podcasts and music radio stations. It looks like AudioValley may be relaunching Winamp as a streaming platform and using the brand to attract attention.

DuckDuckGo Creates A Tool That Prevents Apps From Tracking Your Activity

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In an era when phone users are becoming increasingly aware of the phenomenon of data tracking, names like DuckDuckGo are gaining popularity. The search engine's newest tool will prevent apps from tracking your activity. The tool is called App Tracking Protection and it gives you the option to opt out of tracking.

The new tool is not part of Android, nor does it come in the form of an individual app. Instead, it's integrated into the DuckDuckGo browser and protects your phone even if you're not using the browser. In an official blog post, the company says its new tool will block trackers it identifies in apps from third-party companies.

Once you enable App Tracking Protection, it will run in the background as you go about your daily tasks. The tool recognises when an app is preparing to send data to a third-party tracker and prevents this transfer, so data remains stored locally.

DuckDuckGo claims that work will continue to identify as many such trackers as possible in an attempt to stop any data transfer from your phone. The graphical interface of this tool will also show you which apps are trying to forward your data, along with the location to which it would be sent.

Beautiful CSS Gradient Text

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The CSS

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The Demo

Inspo: MarK Carr

Jordan Peterson Completely Destroys Feminist Narrative

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Helen Lewis interviews Canadian academic and bestselling author Jordan Peterson about the patriarchy, the alt-right, gay parenting, fascist ideologies, his all-beef diet and much more... See the full interview here.

Helen Lewis: So that's my idea of pariarchy, which is a system of male dominance of society.

Jordan Peterson: Yeah, but that's not my sense of the patriarchy.

Helen Lewis: So what is yours?

Jordan Peterson: Well in what sense is our society male-dominated?

Helen Lewis: The fact that the vast majority of wealth is owned by men, the vast majority of capital is owned by men. Women do more unpaid labor...

Jordan Peterson: A very tiny proportion of men and a huge proportion of people who are seriously disaffected are men, most peope in prison are men, most people who are on the street are men, most victims of violent crime are men, most people who commit suicide are men most men most people who died in wars are men, people who do worse in school are men, it's like... Where is the dominance here precisely?

What are you're doing is you're taking a tiny substrata of hyper succesful men and using it to represent the entire structure of the western society. There's nothing about that's vaguely appropriate.

Helen Lewis: But I could say equally most rape victims are women. Terrible things happen to people of both sexes.

Jordan Peterson: And you could say that with perfect utility, but that doesn't provide any evidence for the existence of a male-dominated patriarchy. It just means that terrible thnigs happen to both genders which they certainly do.

Helen Lewis: But there are almost no women wh rape men, for example. So that is an asymmetry there in sexual violence.

Jordan Peterson: Well yes, there's an asymmetry in all sort of places, but that doesn't mean that western cuture is a male-dominated patriarchy. The fact that there are asymetries has nothing to do with your basic argument.

Helen Lewis: No, but you might...

Jordan Peterson: This is a trope that people just accept. Western societies of male-dominated patriarchy it's like no, it's not. That's not true. And even if it has a patriarchal structure to some degree, the fundamental basis of that structure is not power, it's competence! That's why our society works. It's only when a structure degenerates into tyranny that the fundamental relationships between people become dependent on power. It's not power!

If you hire a plumber, who's likely to be male, it's not because there's roving bands of tyrannycal plumbers forcing you to make that choice. And it's the case with almost every interaction that you have at the face of our culture. You're dealing with people who are offering a service of one from another who are usually part of the broad middle class and who offer, and what you're looking for is the person who can offer the best service. And you can find it! It's not a consequence of being dominated by anything that's tyrannical.

And then again, our cuture, our western culture, which is by no means perfect and certainly has tyrannical elements like all cultures do, is the least tyrannical society that's ever been produced and certainly the least tyrannical society exists now. This whole of patriarchy thing... I think you have no idea how prenicious and dangerous it is.

Helen Lewis: Well, no I don't...

Jordan Peterson: Men and women, throughout history have fundamentally cooperated to push back the absolute catastrophe of existence. A terrible death rate that probablity of chronic starvation, early death, disease, the difficulty of raising children with all the death that was associated with that. And to look backwards in time and say, way basically what happened was men took the upper hand and persecuted women in this thyrannical patriarchy it's absolutely misreading of history. It's a terrible thing to teach young women and it's a horrible thing to inflict upon men...

# 5 Halloween Eye-Catching Color Schemes

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Halloween Color Scheme #1

Marigold Yellow / #f8d37b

Terracotta / #de874b

Fountain Blue / #67c3b4

Tradewind / #50a99e

Bitter / #82857b

Halloween Color Scheme #2

Straw / #d5c98b

Di Serria / #dc9855

Raw Sienna / #cd7833

Thatch / #b49292

Coral Tree / #a5665c

Haloween Color Scheme #3

Chalky / #efd198

Pharlap / #a5898c

Red Damask / #d96c42

Roof Terracotta / #a73a26

Buccaneer / #582c2e

Halloween Color Scheme #4

Cold Turkey / #d3bec3

Tulip Tree / #eeb742

Burnt Sienna / #e38940

Muddy Waters / #bd7f58

Ferra / #77525e

Halloween Color Scheme #5

Santa Fe / #aa6e56

Goldenrod / #fbd265

Tan Hide / #fa9e4c

Tango / #ec6d27

Cinnabar / #e64c1d